Job Description

Overview

Director, Biology and Translational Research San Francisco, CA Hybrid

GondolaBio is a clinical-stage biopharmaceutical company focused on developing next-generation therapeutics for genetic diseases. Located on the Stanford Life Sciences campus, GondolaBio fosters a hybrid environment where top scientists collaborate with senior leadership and advisors to blend industry expertise with academic innovation.

About BridgeBio

BridgeBio is a biopharmaceutical company founded to discover, create, test, and deliver transformative medicines to treat patients with genetic diseases and cancers with clear genetic drivers. The company has built a portfolio of drug development programs across multiple therapeutic areas, with two approved drugs.

Responsibilities

• Lead the biology, pharmacology, and translational research for Portal
• Develop deep understanding of the biology and pharmacology of the relevant disease area and treatment approaches
• Responsible for generating comprehensive biology and pharmacology package
• Design, execute, and interpret preclinical studies to address mechanism of action and translational pharmacology studies (in vitro and in vivo)
• Manage relationships with CROs for efficient execution of all the preclinical and translational studies
• Collaborate with cross-functional teams, including DMPK, toxicology, clinical development and regulatory to advance our therapeutic candidates from preclinical stages toward clinical development
• Develop scientific publications, abstracts, and posters, and investor and layperson-facing materials on the Portal program
• Evaluate expansion indications or additional therapy opportunities
• Represent the program scientifically to internal and external audiences
• Manage research associate or scientist-level individuals as needed
• Contribute to the drafting of translation- and pharmacology-related sections of regulatory documents including INDs
• Contribute to due diligence and gap analysis on potential new GondolaBio assets

Values & Team Culture

• Patient Champions, who put patients first and uphold strict ethical standards
• Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset
• Truth Seekers, who are detailed, rational, and humble problem solvers
• Individuals Who Inspire Excellence in themselves and those around them
• High-quality executors, who execute against goals and milestones with quality, precision, and speed

Education, Experience & Skills Requirements

• Ph.D., MD, or Ph.D. / MD degree and expertise in a relevant scientific field with 6+ years of related work experience in pharma or biotech environment
• Strong scientific background and achievements in bioscience and translational, ideally demonstrated by scientific publications, presentations, and / or patents
• Proven track record of successfully leading research programs and teams
• Strong understanding of drug discovery and development processes
• Excellent communication, leadership, and organizational skills
• Ability to think strategically and execute effectively
• Experience in collaborating with cross-functional teams and external partners
• Knowledge of regulatory requirements and industry standards
• Demonstrate creative 'out of the box' thinking to solve complex technical problems and champion innovative technologies to achieve project goals
• Commitment, drive, and ownership mindset

What We Offer

• Patient Days, where we hear directly from individuals living with the conditions we are seeking to impact throughout the year
• A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
• A decentralized model that enables our program teams to focus on advancing science and helping patients
• A place where you own the vision both for your program and your own career path
• A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
• Access to learning and development resources to help you get in the best professional shape of your life
• Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
• Flexible PTO
• Rapid career advancement for strong performers
• Commitment to Diversity, Equity & Inclusion

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